Echocardiographic indices of right ventricular function differentiate pre- and post-capillary pulmonary hypertension

Abstract Funding Acknowledgements Type of funding sources: Foundation. Main source(s): Heart and Lung foundation Background The importance assessing right ventricular (RV) function in heart failure is well established. Methods evaluating intrinsic RV using Doppler echocardiography estimating -pulmonary coupling assessment might improve the understanding response due to increase afterload different conditions. Aim To investigate RV-pulmonary patients with pre- postcapillary pulmonary hypertension. Material We investigated 85 hypertension (PH) defined as mPAP >20mmHg from catheterization (RHC). Those having PH PCWP≤15mmHg PVR ≥ 3WU were categorized pre-capillary (preCPH, n=60) those PCWP>15mmHg <3WU post-capillary (postCPH, n=25). Of 25 postCPH, 16 had HFrEF (LVEF<50%) 9 HFpEF )LVEF≥50%). RHC done simultaneously. Results Pulmonary artery acceleration time (<0.01), sPAP (<0.01) regional strain ( p<0.05) differed between whereas did not, table 1. indirect echocardiographic measure demonstrating strongest association Ees/Ea (volume method= SVrhc/ESVecho) preCPH was mPAP/CO (r=0.61, fig 1A), s’/sPAP RVGLS/sPAP (r=0.62, 1B, 0.57 respectively). e’, segmental global lower compared but not differ groups. Conclusion Right ventricular-pulmonary free wall low accuracy differentiate post CPH which case for PAAt, strain. RVs’/sPAP suggests promise markers ventricular- coupling, especially pre CPH.